Biologically relevant motifs
WebDec 23, 2024 · Jun Yang, Federico Ariel, Dong Wang, Plant long non-coding RNAs: biologically relevant and mechanistically intriguing, Journal of Experimental Botany, Volume 74, Issue 7, 9 April 2024, ... (IPS1), had a 23-nt motif complementary to miR399 and functioned as the target mimic of miR399, sequestering miRNA399 away from its … WebOct 18, 2024 · Below the two exons, the motifs are represented by the PDB structures of 3MJH and 1WJ0, mapped using HHPRED. ... However, some alternative protein isoforms are also biologically relevant 34,35 ...
Biologically relevant motifs
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Webcommon motifs "annotated" with biologically relevant data (motifs with experimentally verified functions). It consists of three major parts (Figure 1). The central part of the project is a novel program, which is implemented by us and called "MotifScan". MotifScan differs from other motif finding programs in important ways. WebNov 1, 2004 · We show that the module cores, the parts with the highest intramodular connectivity, are biologically relevant components of the networks. These constituents correlate only weakly with other levels of organization. ... In the case of the 5' motifs, the statistic measures the number of regulatory motifs common to at least more than half of …
WebMay 1, 2008 · The motif discovery portion of the ELM resource has added conservation, and structural attributes have been incorporated to aid users to discriminate biologically relevant motifs from stochastically occurring non-functional instances. WebNov 21, 2011 · The motif discovery portion of the ELM resource has added conservation, and structural attributes have been incorporated to aid users to discriminate biologically relevant motifs from ...
WebThis can be achieved by using macrocyclization to constrain peptides into their unique and bioactive conformations. Macrocyclic-based designs of biologically relevant peptides may be informed by the patterns of hydrogen bonding observed in X-ray crystal structures. Covalent surrogates of hydrogen bonds reduce entropy by destabilizing unfolded ... WebBiologically relevant data might not show as significant in indiscriminate datasets. What seems obvious is not necessarily what has been retained in the historical process of Natural Selection.
WebMay 16, 2024 · Identification of biologically relevant motifs from MetaChrom. To better understand what have been learned by our model, we extracted representative sequence patterns from our model using TF-MoDISco and TOMTOM (See Method 4.9). To focus on cell-type specific sequence features, we first sampled DNA sequence bins from our test …
WebMay 14, 2024 · Identification of biologically relevant motifs in proteins is a long-standing problem in bioinformatics, especially when considering distantly related proteins where sequence analysis alone becomes increasingly difficult. Here we present a novel approach to identify such motifs in protein three-dimensional structures without depending on se- iowa firefighters memorial coralville iaWebJul 7, 2009 · A unique motif GX{P}[LMQ]X{P}XX{P}X{CIMPVW} was identified as a sufficient condition for peptide binding to Ydj1p. Yeast proteome screen revealed that the motif is biologically relevant and could be observed in many proteins involved in cochaperone activity, with Ydj1p and others involved in critical cellular events. iowa fireworks sales locationsWebApr 21, 2024 · The fact that these motifs represent many of the known functional components of gammaproteobacterial oriC sequences further supports the finding that … iowa fire marshal websiteWebMar 16, 2024 · Fig. 5: Scope of diarylation of biologically relevant motif coupled alkynes and synthetic applications. All reactions are carried out on a 0.2 mmol scale. All the compounds are isolated as a ... opb854a3WebSep 6, 2012 · This highlights a caveat in predicting expression from motifs; while we can identify biologically relevant motifs, this type of analysis only suggests a subset of … iowa fireworks company llcWebSep 27, 2024 · Introduction. Biopolymers, such as DNA and protein, perform varying functions based on their primary sequence. Short, repeated sequences, or “motifs” represent functional units within biopolymers that … op babies\u0027-breathWebJul 7, 2009 · A unique motif GX{P}[LMQ]X{P}XX{P}X{CIMPVW} was identified as a sufficient condition for peptide binding to Ydj1p. Yeast proteome screen revealed that the … op baby\u0027s-breath