Cthrc1 gene

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August undefined, 2024

Web屈振杰，崔琴. 内蒙古包钢医院1.肿瘤内科；2.消化内科，内蒙古包头 014010. 胃癌是消化道常见的恶性肿瘤，其发病率及死亡率居恶性肿瘤第2位[1]。 WebMar 1, 2024 · Expression of CTHRC1 in Patients With COAD Under Different Physiological or Pathological States. UALCAN analysis showed that the expression level of CTHRC1 was significantly higher in the patients with primary COAD than that in normal tissues ().Notably, this abnormally high expression pattern is generally applicable to patients with different …

Single-Cell RNA Sequencing Analysis Reveals a Crucial …

WebDec 1, 2001 · Disease susceptibility is associated with variants affecting the gene represented in this entry Description A condition characterized by a metaplastic … WebGenomic Mutations. 2 involving Cthrc1. Incidental Mutations. Mutagenetix , APF. Find Mice (IMSR) 20 strains or lines available. Comparison Matrix. Gene Expression + Phenotype. … how do you say infinity

CTHRC1 expression is a novel shared diagnostic and prognostic biomarker ...

WebOct 8, 2012 · Background We discovered the gene Collagen Triple Helix Repeat Containing 1 (Cthrc1) and reported its developmental expression and induction in adventitial cells of injured arteries and dermal cells of skin wounds. The role of Cthrc1 in normal adult tissues has not yet been determined. Methodology/Principal Findings We … WebELISA Kits by Target . ELISA (enzyme-linked immunosorbent assay) is a plate-based technique for detection and quantification of antibodies or proteins such as cytokines, chemokines, growth factors, hormones, and intracellular phosphorylated proteins. WebFeb 22, 2007 · We identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene expressed in the adventitia and neointima on arterial injury and found that it functionally increases cell migration while reducing collagen deposition. To address the in vivo role of Cthrc1, we generated transgenic mouse lines that constitutively overexpress … how do you say infrastructure

Cthrc1 Is a Positive Regulator of Osteoblastic Bone Formation

Frontiers CTHRC1 Is a Prognostic Biomarker and

WebSep 9, 2008 · Methodology/Principal Findings. We identified collagen triple helix repeat containing-1 (Cthrc1) as a downstream target of bone morphogenetic protein-2 (BMP2) in osteochondroprogenitor-like cells by PCR-based suppression subtractive hybridization followed by differential hybridization, and found that Cthrc1 was expressed in bone … WebSep 21, 2011 · Orloff et al. (2011) identified a germline 131A-C transversion in exon 1 of the CTHRC1 gene, resulting in a gln44-to-pro (Q44P) substitution, in 1 (1.1%) of 116 patients of European descent with Barrett esophagus and/or esophageal adenocarcinoma ().The mutation was not found in 125 controls. The same mutation was found in 1 (1.7%) of 58 … phone number to ptcbWebBackground: We discovered the gene Collagen Triple Helix Repeat Containing 1 (Cthrc1) and reported its developmental expression and induction in adventitial cells of injured … phone number to post office

"WebOct 8, 2012 · Generation of Cthrc1 null mice. (A) Cthrc1 gene targeting schematic showing replacement of exons 2-4 with a PGK-neo cassette. (B) Embryonic stem cell targeting with Southern blot analysis of ... " - Cthrc1 gene

Cthrc1 gene

WebJan 29, 2013 · Colorectal cancer (CRC) patients with peritoneal carcinomatosis (PC) have a poor prognosis. Over the last decade, increasing evidence has suggested that the Collagen Triple Helix Repeat Containing 1 (CTHRC1) gene is involved in cancer progression and invasion. In this study, we investigated the expression of CTHRC1 in CRC and its … WebAug 7, 2024 · We reveal gene expression signatures that demarcate fibroblasts from mural cells and provide molecular signatures for cell subtype identification. ... C1qtnf3, and Cthrc1) their distribution in ...

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WebJul 29, 2013 · Collagen triple helix repeat containing-1 (CTHRC1) is a secreted glycoprotein that activates the planar cell polarity pathway of Wnt signaling. Using microarray analysis, we found that the CTHRC1 gene is overexpressed in hepatocellular carcinoma (HCC). The level of CTHRC1 mRNA was measured in 201 surgically resected … WebMar 21, 2024 · CTHRC1 (Collagen Triple Helix Repeat Containing 1) is a Protein Coding gene. Diseases associated with CTHRC1 include Barrett Esophagus and Adenocarcinoma . Among its related pathways are Wnt …

WebWe recently identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene induced in adventitial fibroblasts after arterial injury. Cthrc1 is a 30 kDa secreted protein that has the ability to inhibit collagen matrix synthesis. Cthrc1 is also glycosylated and retains a signal sequence consistent with the presence of Cthrc1 in the ... WebFeb 8, 2024 · Introduction. The collagen triple helix repeat containing 1 (Cthrc1) gene was first reported by the Lindner laboratory in a screen for genes differentially expressed upon major damage to arteries in rats (Pyagay et al. 2005).Cthrc1 was highly induced in injured arteries, with expression subsiding upon healing (Pyagay et al. 2005; LeClair et …

WebMay 13, 2024 · A Relative mRNA level of CTHRC1 in primary CRC with metastasis (Mets) and primary CRC without (w/o) Mets using three … WebOct 6, 2024 · According to the previous reports, the collagen triple helix repeat containing 1 (CTHRC1) causes tumorigenesis by modulating the tumor microenvironment, however, the evidence is limited to a few human cancer subtypes. ... (GEO) based datasets. During the analysis, we simply queue the CTHRC1 gene in these databases to acquire the KM …

WebGene view. The gene view histogram is a graphical view of mutations across CTHRC1. These mutations are displayed at the amino acid level across the full length of the gene …

WebAug 30, 2024 · Gene ID: 68588, updated on 30-Aug-2024. Summary Other designations. collagen triple helix repeat-containing protein 1. GeneRIFs: Gene References Into … how do you say inhale in spanishWebMar 20, 2024 · The collagen triple helix repeat containing 1 (CTHRC1) gene is located on human chromosome 8q22.3 and was initially identified in balloon injury and normal rat … how do you say inhaler in spanishWebCTHRC1 is a Potential Prognostic Biomarker and Correlated with Macrophage Infiltration in Breast Cancer . Fulltext; Metrics; Get Permission; Cite this article; Authors Wang Z, Zhang S, Zheng C, Xia K, Sun L, Tang X, Zhou F, Ouyang Y, Tang F. Received 13 March 2024. how do you say inguinal herniaWebCTHRC1. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. CTHRC1 INFORMATION. Proteini. Full gene name according to HGNC. Collagen triple … how do you say information in spanishWebFeb 22, 2007 · We identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene expressed in the adventitia and neointima on arterial injury and found that it functionally increases cell migration while reducing collagen deposition. To address the in vivo role of Cthrc1, we generated transgenic mouse lines that constitutively overexpress … how do you say ingrown nail in spanishWebAug 12, 2024 · Collagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. CTHRC1 expresses mainly in adventitial fibroblasts and … how do you say ingenuity how do you say injection in spanish